A survey of antibacterial drug utilization in 44 patients with nosocomial infections
10.3760/j.issn.1008-5734.2000.04.007
- VernacularTitle:44例医院感染病例的抗菌药物利用调查
- Author:
Suiping HE
1
;
Jianwei LI
;
Yanli QUAN
;
Yanru HUAN
Author Information
1. 北京积水潭医院,北京,100035
- Publication Type:Journal Article
- Keywords:
antibacterial drug utilization;
nosocomial infections;
investigation
- From:
Adverse Drug Reactions Journal
2000;2(4):232-235
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To understand the condition of the antibacterial drug utilization and the effects of these drugs on the nosocomial infections.Methods:The data of 44 patients of the nosocomial infections were in entry and statistical analysis with a software of pharmacoepidemiology.Results:In 44 cases,the frequency of antibacterial administration was 88.64％ before nosocomial infections,31.86％ for preventive purposes and 33.63％ for unreasonable application.Moreover,the microbiological assay and drug sensitive test were not done in 95.5 ％ of the cases before antibacterials taken.The nosocomial infections mosdy occured in the patients who took the drugs for a long time,the gastrointestinal infections standing first on the list.In 8 risk factors of the nosocomial infections,the constitutive ratio and afterwards infection rate of the broadspectrum antibacterial utilization were 29.06 ％ and 3.93 ％,ranking the first and the seventh,respectively.Conclution:Antibacterials are empirically used in clinic for both prevention and treatment with less attention to the microbiological assay and the drug sensitive test.The administration of antibacterials is a protective factor,and one of the risk factors for the nosocomial infections,too.
