Olfactory dysfunction and common neurocognitive disorder: an update of research progression
10.3760/cma.j.cn113661-20190426-00151
- VernacularTitle:嗅觉障碍与常见神经认知障碍的研究进展
- Author:
Lihui TU
1
;
Huali WANG
1
;
Xin YU
1
Author Information
1. 北京大学第六医院临床研究室 北京大学精神卫生研究所 国家精神心理疾病临床医学研究中心 国家卫生健康委员会 精神卫生学重点实验室（北京大学）100191
- Publication Type:Journal Article
- Keywords:
Alzheimer′s disease;
Olfactory dysfunction;
Cognitive impairment
- From:
Chinese Journal of Psychiatry
2020;53(2):155-158
- CountryChina
- Language:Chinese
-
Abstract:
Olfactory dysfunction has a high prevalence in the elderly, which not only affects people′s quality of life and mental health but also is a clinical manifestation of neuropsychiatric diseases, especially of neurocognitive disorders (e.g., Alzheimer′s disease (AD)). AD is a common neurodegenerative disease which is mainly characterized by progressive dementia and cannot be cured.It could impose heavy burden on patients, families and society. Screening AD-related biomarkers can greatly benefit the early diagnosis and treatment of AD and further delay the progress of the disease. Olfactory impairment is closely related to mild cognitive impairment (MCI) and AD. Olfactory screening tests could help the early identification of these disorders. Therefore, this article aims to review the latest researches on the association between olfactory dysfunction and conventional diagnostic methods of MCI and AD, and further evaluate the research value of olfactory impairment in studies of common neurocognitive disorders.
