Adams-Stokes syndrome induced by carbamazepine
10.3760/cma.j.issn.1008-5734.2017.01.019
- VernacularTitle:卡马西平致阿-斯综合征
- Author:
Wenjun YU
1
;
Cuiting QIU
;
Weijia QING
;
Na LI
Author Information
1. 解放军第三〇六医院急诊部, 北京,100101
- Publication Type:Journal Article
- Keywords:
Carbamazepine;
Adams-Stokes syndrome
- From:
Adverse Drug Reactions Journal
2017;19(1):69-71
- CountryChina
- Language:Chinese
-
Abstract:
A 74-year-old female patient received oral carbamazepine 0. 1g thrice daily because of epilepsy after acute ischemic stroke. On the third day, the patient suddenly presented drowsiness which gradually aggravated to a state of mild coma within 30 minutes. The electrocardiogram showed that sick sinus syndrome and junctional rhythm with a heart rate of 34 beats per minute. The patient was diagnosed as Adams-Stokes syndrome which may be induced by carbamazepine. She was given an intravenous injection of atropine sulfate 0. 5 mg immediately. Then atropine sulfate 1 mg in 5% glucose injection 500 ml was slowly given by intravenous drip. Two hours later, the patient regained consciousness. The electrocardiogram showed restoration of sinus rhythm with a heart rate of 48 beats per minute. Carbamazepine was withdrawn and disturbance of consciousness did not recur.
