Hypoglycemic coma due to insulin dose conversion error
10.3760/cma.j.issn.1008-5734.2017.01.020
- VernacularTitle:胰岛素剂量换算错误致低血糖昏迷
- Author:
Ying LIU
1
;
Liping LIU
;
Wangjun QIN
;
Min MAO
Author Information
1. 中日友好医院药学部, 北京,100029
- Publication Type:Journal Article
- Keywords:
Insulin;
Hypoglycemia
- From:
Adverse Drug Reactions Journal
2017;19(1):72-73
- CountryChina
- Language:Chinese
-
Abstract:
A 79-year-old female patient with type 2 diabetes was ordered to receive subcutaneous injection of biosynthetic human insulin injection 8 U [ Novolin R 3 ml:300 U ( cartridge) ] before 3 meals. Because of no matching insulin pen, the nurse used normal insulin syringe ( 40 U/ml, 0. 2 ml contains common insulin injection 8 U) as a substitution of Novolin R insulin pen and gave the patient an injection of 0. 2 ml Novolin R liquid ( including Novolin R 20 U) according to her experience of using normal insulin syringe formerly. About 4 hours later, the patient developed sweating, coma, and no responses to call. Her fingertip blood glucose was 2. 8 mmol/L. She received an intravenous injection of 50% glucose 40 ml immediately. About 10 minutes later, her fingertip blood glucose increased to 4. 4 mmol/L. About 70 minutes later, her fingertip blood glucose increased to 6. 0 mmol/L and her consciousness recovered.
