Research progress of structural and functional changes in the fundus in patients with schizophrenia
10.3760/cma.j.cn113661-20220728-00207
- VernacularTitle:精神分裂症患者眼底结构和功能改变研究进展
- Author:
Yan WANG
1
;
Cong LI
;
Yun REN
;
Hanpeng ZHAO
;
Zhenchao DU
;
Xue HE
;
Jianrong JIANG
;
Lei LIU
;
Xiaohong YANG
Author Information
1. 华南理工大学医学院，广州510006
- Publication Type:Journal Article
- Keywords:
Schizophrenia;
Tomography, optical coherence;
Electroretinography;
Fundus photography;
Optical coherence tomography angiography
- From:
Chinese Journal of Psychiatry
2023;56(3):193-198
- CountryChina
- Language:Chinese
-
Abstract:
Previously, the diagnosis of schizophrenia was empirical since it relied on the patient′s subjective symptoms and the practitioner′s clinical experience. There is an urgent need for objective and reproducible assessment tools to aid its diagnosis. Changes in brain structure and function are closely related to the development of schizophrenia. The retina, a part of the central nervous system, is highly similar to the brain morphologically and neurophysiologically and can be assessed by a non-invasive and convenient fundus examination. There have been studies using optical coherence tomography, fundus photography, optical coherence tomography angiography, and electroretinography to identify significant changes in the structure and function of the fundus in patients with schizophrenia. However, there is still a lack of generalization in these studies. This article summarises and discusses the findings in this area and presents a vision for future studies to explore the application value of fundus in the management of schizophrenia.
