Cortical activation during obstacle avoidance in convalesent stroke patients:A fNIRS study
10.3969/j.issn.1001-1242.2025.03.010
- VernacularTitle:基于功能性近红外光谱技术探索脑卒中恢复期患者障碍躲避时皮层激活的相关性研究
- Author:
Jiay-an MAO
1
;
Xinyuan WANG
;
Wenbing LIU
Author Information
1. 浙江中医药大学附属康复医院(浙江康复医疗中心),浙江省 杭州市,310052;浙江中医药大学第三临床医学院、康复医学院
- Publication Type:Journal Article
- Keywords:
convalescent stroke;
obstacle avoidance;
functional near-infrared spectroscopy;
cortical activation
- From:
Chinese Journal of Rehabilitation Medicine
2025;40(3):382-388
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore cortical activation during the obstacle avoidance task in convalescent stroke patients,and examine the effect of obstacle avoidance difficulty on brain activation.Method:A total of 20 convalescent stroke patients were recruited to perform various motor tasks,including walking,simple obstacle avoidance,difficult obstacle avoidance,and motor imagery.Functional near-infrared spectroscopy(fNIRS)was used to detect the oxygenated hemoglobin concentration in the prefrontal cortex(PFC),premotor cortex(PMC)and supplementary motor area(SMA)of the patients.Additional relevant sec-ondary indicators were evaluated and collected.Statistical analysis was performed without grouping and with grouping.Result:The activation levels of bilateral PFC,PMC and SMA during the dynamic task were significantly dif-ferent from those during the static tasks(P＜0.05),with the highest activation observed in the PFC.There were significant differences between simple and difficult obstacle avoidance tasks in the unaffected-side SMA(P＜0.05).In addition,there was a linear positive correlation between the peak activation level of PMC on the unaffected side and Tinetti score(P＜0.05).Conclusion:Bilateral PFC,PMC and SMA are involved in limb movement in convalescent stroke patients,with PFC showing the highest level of activation.In addition,SMA on the unaffected side may contribute to regulating the difficulty of obstacle avoidance.Moreover,the peak activation level of PMC on the unaffected side is associated with balance and walking function.
