Analysis of clinical phenotypes of bipolar disorder with mixed states diagnosed using ICD-10 and DSM-5
- VernacularTitle:ICD-10与DSM-5诊断双相障碍混合状态的临床表型分析
- Author:
Yang LI
1
;
Jia ZHOU
;
Zuowei WANG
;
Yuncheng ZHU
;
Guiyun XU
;
Miao PAN
;
Zhiyu CHEN
;
Wenfei LI
;
Zhian JIAO
;
Mingli LI
;
Yong ZHANG
;
Jingxu CHEN
;
Xiuzhe CHEN
;
Na LI
;
Jing SUN
;
Jian ZHANG
;
Shaohua HU
;
Haishan WU
;
Zhaoyu GAN
;
Yan QIN
;
Yumei WANG
;
Yantao MA
;
Xiaoping WANG
;
Xiaohong LI
;
Yiru FANG
Author Information
- Publication Type:Journal Article
- Keywords: Bipolar disorder; Diagnostic criteria; Mixed episode; Mixed feature
- From: Chinese Journal of Psychiatry 2023;56(4):267-275
- CountryChina
- Language:Chinese
- Abstract: Objective:This study investigates the difference in the detection rate and symptomatology between ICD-10 and DSM-5 diagnostic criteria for bipolar disorder with mixed states.Methods:Based on the Phase Ⅰ (2012) and Phase Ⅱ (2021) databases of National Bipolar Mania Pathway Survey (BIPAS), patients with bipolar disorder were included. General demographic data, clinical characteristics, symptomatic phenotypes, and mixed characteristics were retrieved. The detection rates and symptomatic performances of patients with or without mixed states in Phase Ⅰ and Ⅱ were compared using the chi-square test.Results:For patients with mixed states, the detection rate during Phase Ⅱ (2021) using DSM-5 (18.79%, 199/1 059) criteria was significantly higher than that during Phase Ⅰ (2012) using ICD-10 (6.78%, 199/2 934; χ 2=125.05, P<0.001). Whether using ICD-10 or DSM-5 criteria, patients with mixed states had a significantly higher frequency of multiple symptomatic manifestations. Conclusion:The DSM-5 diagnostic criteria generate a high detection rate for bipolar disorder with mixed states. The clinical phenotypes of bipolar disorder with mixed states vary significantly using different diagnostic tools.
