Gingival hyperplasia due to amlodipine
10.3760/cma.j.issn.1008-5734.2015.06.014
- VernacularTitle:氨氯地平致牙龈增生
- Author:
Lulu QIU
1
;
Huiyi LYU
1
Author Information
1. 160027,大连医科大学附属第二医院药学部
- Publication Type:Journal Article
- Keywords:
Amlodipine;
Gingival hyperplasia
- From:
Adverse Drug Reactions Journal
2015;(6):455-455
- CountryChina
- Language:Chinese
-
Abstract:
A 73-year old woman with hypertension received amlodipine(5 mg once daily)and bisoprolol(2. 5 mg once daily). One year later,she developed the symptoms of gingival swelling,bleeding, and difficult to chew and occlude. She was diagnosed as gingival hyperplasia by a doctor of department of stomatology and underwent resection of gingiva that had hyperplasia. The patient could chew 5 days after the operation. The patient' s gingival hyperplasia was considered as amlodipine-induced gingival overgrowth. Amlodipine was withdrawn and use of hydrochlorothiazide was started,but bisoprolol was continued. The result of return visit 6 months after operation showed the symptoms of gingiva,swelling and bleeding did not occur again,and the blood pressure was controlled stablely.