A case report of the treatment options for a patient with treatment-resistant schizophrenia
10.3760/cma.j.cn113661-20221229-00355
- VernacularTitle:难治性精神分裂症患者1例的治疗选择
- Author:
Xin LI
1
;
Xiaobo HUANG
1
;
Guowei WU
1
Author Information
1. 中南大学湘雅二医院精神卫生研究所 国家精神心理疾病临床医学研究中心，长沙410011
- Publication Type:Journal Article
- Keywords:
Schizophrenia;
Bunanserin;
Side effects
- From:
Chinese Journal of Psychiatry
2023;56(5):378-381
- CountryChina
- Language:Chinese
-
Abstract:
This article describes a female patient with treatment-resistant schizophrenia (TRS) who experienced persistent auditory hallucinations and self-laughter. Despite receiving adequate amounts and courses of risperidone and aripiprazole, the patient′s symptoms remained poorly controlled. The combined use of amisulpride and olanzapine resulted in hypotension and elevated levels of amisulpride in the blood. However, after switching to bunanserin in combination with low-dose olanzapine, the patient′s symptoms improved significantly. This case report aims to guide the rational use of medication in TRS patients who have poor tolerance to traditional therapies.
