Research progress of mesenchymal stem cells and exosomes in the treatment of autism spectrum disorders

VernacularTitle:间充质干细胞及其外泌体治疗孤独症谱系障碍的研究进展
Author: Cheng YANG ¹ ; Lei XIA ¹ ; Yinghan TIAN ¹ ; Lewei LIU ¹ ; Huanzhong LIU ¹
Author Information

1. 安徽医科大学附属巢湖医院　安徽医科大学精神卫生与心理科学学院　安徽省精神医学中心，合肥238000
Publication Type:Journal Article
Keywords: Autistic disorder; Mesenchymal stem cells; Mesenchymal stem cell exosomes
From: Chinese Journal of Psychiatry 2023;56(2):150-154
CountryChina
Language:Chinese
Abstract: Autism Spectrum Disorder (ASD) is a severe neurodevelopmental disorder. Its pathophysiological mechanism remains unclear. To date, the common therapeutic interventions for ASD are symptomatic drug treatment and rehabilitation training. More effective therapeutic methods are urgently in need. In recent years, accumulated studies have been conducted on stem cell therapy for ASD, especially mesenchymal stem cells (MSCs), which may play an important role in the therapeutic effect of MSCs through their secreted exosomes. This article reviews the progress of MSCs and MSC-sourced exosomes (MSC-Exos) in treatment of ASD.