Research progress of neuroimmune response in the pathogenesis of the depressive disorder
10.3760/cma.j.cn113661-20220701-00171
- VernacularTitle:神经免疫在抑郁症发病机制中的研究进展
- Author:
Rui SUN
1
;
Ge YIN
;
Dingya SUN
;
Li CAO
;
Xiaoying BI
Author Information
1. 海军军医大学第一附属医院神经内科，上海200433
- Publication Type:Journal Article
- Keywords:
Depressive disorder;
Stress;
Immune response;
Inflammation
- From:
Chinese Journal of Psychiatry
2023;56(2):137-143
- CountryChina
- Language:Chinese
-
Abstract:
The pathophysiology of depressive disorder is complex. However, the understanding of its pathogenesis is still relatively limited in previous studies. In recent years, the neuroimmune mechanism has received extensive attention. The bidirectional communication between the central nervous system and the peripheral immune system has been identified to play an important role in depressive disorder. This article reviews the research progress of neuroimmune response in patients with depressive disorders and animal models of depression to raise considerations for the treatment of depressive disorder.
