Suspected 5-serotonin syndrome induced by fluoxetine
10.3760/cma.j.issn.1008-5734.2013.04.015
- VernacularTitle:氟西汀致疑似5-羟色胺综合征
- Author:
Wei-jing MU
1
;
Xiao-lei REN
;
Hai-ying ZHANG
;
Wan-yu FENG
Author Information
1. 100062,北京市普仁医院药剂科
- Publication Type:Journal Article
- Keywords:
Fluoxetine;
Synclonus tremens;
5-serotonin syndrome
- From:
Adverse Drug Reactions Journal
2013;15(4):223-224
- CountryChina
- Language:Chinese
-
Abstract:
A 72-year-old male received fluoxetine 20 mg daily for 24 months for post-stroke depression (PSD) due to cerebral infarction.After eighteen months of treatment,the patient developed synclonus tremens suddenly but without other complicated syndromes.The patient's condition improved spontaneously on the next day and did not leave any discomfort.After twenty-three months of treatment,the patient developed similar synclonus tremens two times again.The results of physical and laboratory examinations showed no obvious abnormality.The result of electrocardiogram examination eliminated the seizures and essential tremor.It was considered the suspected 5-serotonin syndrome induced by fluoxetine.Fluoxetine was stopped and the patient had no recurrence of synclonus tremens.
