Research progress in assessment of allostatic load and its impact on diagnosis and treatment of depressive disorder
10.3760/cma.j.cn113661-20220407-00089
- VernacularTitle:适应负荷的评定及对抑郁症诊疗影响的研究进展
- Author:
Simiao FENG
1
;
Yonggui YUAN
Author Information
1. 东南大学医学院,南京 210009
- Publication Type:Journal Article
- Keywords:
Depressive disorder;
Stress;
Allostatic load;
Allostatic load index;
Biomarkers
- From:
Chinese Journal of Psychiatry
2023;56(1):57-61
- CountryChina
- Language:Chinese
-
Abstract:
Allostatic load is the cost of adjustments of the internal physiological milieu to accommodate external stress. A series of physiological and psychological changes will occur when the stress exceeds an individual′s coping skills, which may further lead to physical damage. Stress plays a major role in the etiology and development of major depressive disorder. The introduction of the concept of allostatic load provides new insight for the prevention, diagnosis and treatment of major depressive disorder. This article discussed the evaluation method of allostatic load and its impact on the diagnosis and treatment of depressive disorder.