Study on evaluation of different diagnostic criteria for metabolic syndrome applied in the population with alcohol use
10.3760/cma.j.cn113661-20220104-00001
- VernacularTitle:男性酒精使用人群不同代谢综合征诊断标准下患病率的研究
- Author:
Ran WANG
1
;
Shuqi XU
1
;
Lan WANG
1
;
Ranran ZHAO
1
;
Xueyi WANG
1
Author Information
1. 河北医科大学第一医院精神卫生中心，石家庄 050031
- Publication Type:Journal Article
- Keywords:
Metabolic syndrome;
Alcohol use;
Diagnostic criteria;
Prevalence rate
- From:
Chinese Journal of Psychiatry
2022;55(4):288-294
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate four different diagnostic criteria for metabolic syndrome(MetS) in the Chinese Northern Population with alcohol use.Methods:Stratified random sampling was used to select male workers in Gaocheng District, Shijiazhuang in 2016. Alcohol Use Disorder Identification Test (AUDIT) was used to assess the risk of any alcohol use disorder. MetS-related physician and laboratory tests were performed. The MetS prevalence rate was calculated according to the diagnostic criteria of the Chinese Diabetes Society (CDS), the National Cholesterol Education Program (NCEP) Adult Treatment Panel-Ⅲ (ATP-Ⅲ), International Diabetes Federation (IDF), and the 2016 Chinese Adult Dyslipidemia Prevention and Control Guidelines, respectively. The CDS criteria were considered the reference standards for evaluating the significance of the other three MetS diagnostic criteria in disease screening.Results:A total of 1 267 men workers were investigated with a questionnaire, including 1 082 people with alcohol intake. The average age was (35.25±9.48) years. The MetS prevalence rates were 12.94%, 19.96%, 23.75%, and 23.94% according to CDS, NCEP ATP-Ⅲ, IDF, and Chinese Adult Dyslipidemia Prevention and Control Guidelines, respectively. In IDF, the highest prevalence rate of MetS was 18-25 and 35-45 age group; In the 45-68 age group, the highest and most consistent prevalence rate was found on MetS diagnostic criteria of IDF and Chinese Adult Dyslipidemia Prevention and Control Guidelines. MetS prevalence increased with drinking risk in all diagnostic criteria, and the MetS prevalence rate based on the IDF and Chinese Adult Dyslipidemia Prevention and Control Guidelines were higher than the other two. Referring to the CDS, the sensitivities of IDF,NCEP ATP-Ⅲ and Chinese Adult Dyslipidemia Prevention and Control Guidelines were 84.29%, 87.14%, and 92.14%; the specificities were 97.33%, 97.92%, and 98.66%, the positive predictive values were 45.91%, 56.48%, and 49.81%, respectively. Kappa consistency test found that IDF and Chinese Adult Dyslipidemia Prevention and Control Guidelines had the best consistency in total alcohol used population, lower-risk alcohol used population and lower-risk alcohol used population, with the compliance rate of 90.3%( Kappa=0.852),89.7%( Kappa=0.844) and 91.0%( Kappa=0.867). Conclusion:The MetS prevalence rate in the alcohol use population in northern China varies by four diagnostic criteria. The MetS prevalence rate is the lowest on CDS, and the Chinese Adult Dyslipidemia Prevention and Control Guidelines give the highest MetS prevalence rate with the best sensitivity and specificity for diagnosing the MetS.
