Kleine-Levin Syndrome:a case report
10.3760/cma.j.cn113661-20211121-00336
- VernacularTitle:克莱恩-莱文综合征1例
- Author:
Shuwei HU
1
;
Yun MO
;
Xiaohui YUAN
;
Gang WU
;
Juan PENG
Author Information
1. 遵义医科大学,遵义 563006
- Publication Type:Journal Article
- Keywords:
Kleine-Levin Syndrome;
Anorexia;
Bulimia;
Hypersomnia
- From:
Chinese Journal of Psychiatry
2022;55(3):241-244
- CountryChina
- Language:Chinese
-
Abstract:
Kleine-Levin Syndrome (KLS), also known as "sleeping Beauty Syndrome", is characterized by a typical triad of recurrent episodes of hypersomnia, bulimia, and hypersexuality, which may be accompanied by behavioral or cognitive dysfunction and affective disorders. During the intermittent period, patient′s all functions remain intact. At present, the pathogenesis of the disease, auxiliary examination that are beneficial for diagnosis and effective treatment plans are not clear. Due to the possible genetic differences in different regions and populations, the clinical manifestations of the disease are various, which can easily lead to misdiagnosis. According to previous studies, about 66% of the abnormal eating in KLS patients are bulimia, however, anorexia is more common in China. In this case, an 11-year-old Chinese male patient with KLS presented anorexia behaviors in the first 10 months since diagnosis, and changed to bulimia in the subsequent 6 months follow-up. We carefully investigated his medical history, diagnosis, treatment process and differential diagnosis, in order to provide better insights of the clinical characteristics and diagnosis of KLS.