Inspiratory muscle training for weaning outcomes in patients with weaning failure:a systematic review
10.3969/j.issn.1006-9771.2025.03.007
- VernacularTitle:吸气肌训练对脱机失败者脱机疗效的系统综述
- Author:
Qian CAI
1
;
Xi ZHANG
;
Hairong SU
;
Na LIU
;
Ying HUANG
;
Jiqiang LI
;
Jin'gen XIA
;
Decai ZHENG
Author Information
1. 广州中医药大学第二附属医院,广东 广州市 510006
- Publication Type:Journal Article
- Keywords:
inspiratory muscle training;
weaning failure;
ventilator weaning;
systematic review
- From:
Chinese Journal of Rehabilitation Theory and Practice
2025;31(3):306-313
- CountryChina
- Language:Chinese
-
Abstract:
Objective To systematically evaluate the effect of inspiratory muscle training(IMT)on weaning outcomes in patients with weaning failure.Methods Literatures in Chinese and English were retrieved from databases such as PubMed,Cochrane Library,Web of Science,Embase,CNKI,VIP,Wanfang data and CBM for researches on the effect of IMT in mechanical ventila-tion weaning failure,from the inception of the databases to October 22,2024.The methodological quality of the researches was evaluated with PEDro scale,and data were extracted for a systematic review.Results Nine randomized controlled trials were included,published between 2011 and 2023,from Brazil,China,the United States,Iran and Australia,with a total of 499 patients.The scores of the PEDro scale ranged five to eight.The population included patients with prolonged weaning,difficult weaning and tracheostomy.The IMT methods included threshold load training and tapered flow resistance training.The training intensity was 30%to 80%of maximal inspiratory pressure(MIP),and some researches did not set the training intensity based on MIP.The pro-gression of intensity varied widely across researches.The intervention frequency ranged from five to 30 breaths per set,with at least one minute rest between sets,two to six sets per session,one to two sessions per day,and five to seven days per week.The duration of the intervention ranged from successful weaning,one week after weaning,extubation,or four days to eight weeks.Regarding the efficacy of the intervention,IMT was not benefi-cial for the duration of mechanical ventilation and intensive care unit(ICU)length of stay on weaning failure pa-tients.However,the effect of IMT on weaning successful rates,duration of weaning,MIP and mortality was in-consistent.Conclusion IMT can not improve the duration of mechanical ventilation and ICU length of stay for weaning failure pa-tients,and there is still debate regarding its effect on successful rate of weaning,duration of weaning,MIP and mortality.