Value of ovarian-adnexal reporting and data system MRI score combined with tumor markers in ovarian tumors
10.3969/j.issn.1002-1671.2025.03.018
- VernacularTitle:卵巢-附件报告和数据系统MRI评分联合肿瘤标志物评估卵巢肿瘤的价值
- Author:
Lamei ZHANG
1
;
Jingtao SUN
;
Qi YANG
;
Shulan YANG
;
Liyuan HAN
Author Information
1. 唐山市妇幼保健院放射科,河北 唐山 063000
- Publication Type:Journal Article
- Keywords:
ovarian-adnexal reporting and data system;
ovarian tumor;
magnetic resonance imaging;
tumor marker
- From:
Journal of Practical Radiology
2025;41(3):438-441
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of ovarian-adnexal reporting and data system(O-RADS)MRI score combined with tumor markers(CA125+HE4)in ovarian tumors.Methods Data from 223 patients with ovarian tumors confirmed by pathology were analyzed retrospectively,including 260 lesions.The Kappa test was used to assess the consistency of O-RADS MRI score between low and high seniority physician groups.The receiver operating characteristic(ROC)curve was drawn to analyze the diagnostic effi-cacy of O-RADS MRI score combined with tumor markers(CA125+HE4)in ovarian tumors.Results The Kappa value of the O-RADS MRI score between low and high seniority physician groups was 0.803[95%confidence interval(CI)0.746-0.860].The sensitivity based on O-RADS MRI score for distinguishing benign and malignant ovarian tumors was 0.957 and 0.989,the specificity was 0.784 and 0.820,the accuracy was 0.846 and 0.881,the positive predictive value was 0.712 and 0.754,and the negative pre-dictive value was 0.970 and 0.993,and the area under the curve(AUC)was 0.871 and 0.905,respectively in the low and high senior-ity physician groups.Combined with tumor markers(CA125+HE4),the sensitivity and negative predictive value of both low and high seniority physician groups were 1.000.Conclusion The O-RADS MRI score has high diagnostic efficacy and good repeatability in ovarian tumors.Combined with tumor markers CA125 and HE4,the O-RADS MRI score can further improve the diagnostic sen-sitivity.
