Metabolic dysfunction and related pathogenesis in bipolar disorder
10.3760/cma.j.cn113661-20211108-00323
- VernacularTitle:双相障碍的代谢障碍及相关发病机制
- Author:
Donghong CUI
1
Author Information
1. 上海交通大学医学院附属精神卫生中心 上海市重性精神病重点实验室，上海 201108
- Publication Type:Journal Article
- Keywords:
Bipolar disorder;
Metabolic dysfunction;
Dystrophia
- From:
Chinese Journal of Psychiatry
2022;55(3):175-181
- CountryChina
- Language:Chinese
-
Abstract:
The brain is the biggest energy hog. The dystrophia and energy metabolic dysfunction will significantly affect the functions of human brain. The potential pathogenesis may lie in the mitochondria dysfunction related to cellular energy disturbance; metabolic abnormalities of glucose, lipid, and protein; thyroid function; nutrient supply; metabolic disorders of vitamin and metallic element. The metabolism hypothesis of bipolar disorder will be gradually elucidated with the further researches, and it will also provide a new strategy for the prevention and treatment of bipolar disorder.
