The evaluation value of whole brain CT perfusion imaging scanning parameters on collateral circulation in ischemic stroke
10.3969/j.issn.1002-1671.2025.03.003
- VernacularTitle:全脑CT灌注成像扫描参数对缺血性脑卒中侧支循环的评估价值
- Author:
Lu JIN
1
;
Xiaoling GUO
;
Tao WANG
;
Tian DONG
;
Changyuan WANG
;
Jun SHENG
Author Information
1. 安徽理工大学第一附属医院CT室,安徽 淮南 232001
- Publication Type:Journal Article
- Keywords:
computed tomography perfusion imaging;
ischemic stroke;
collateral circulation;
cerebral blood flow;
cerebral blood volume;
mean transit time;
time to peak
- From:
Journal of Practical Radiology
2025;41(3):368-371
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the evaluation value of whole brain computed tomography perfusion imaging(CTPI)scanning parameters on collateral circulation in ischemic stroke.Methods One hundred and two patients with ischemic stroke were selected,according to the condition they were divided into mild group(n=26),moderate group(n=56),and severe group(n=20).The col-lateral circulation status was evaluated based on the modified American Society of Interventional and Therapeutic Neuroradiology(ASITN)/Society of Interventional Radiology(SIR)score of dynamic CT angiography,and was divided into good group(n=61)and poor group(n=41).CTPI parameters were compared between different groups of patients with cerebral blood flow(CBF),cerebral blood volume(CBV),mean transit time(MTT),and time to peak(TTP).Results The CBF and CBV in the severe group were lower than those in the mild and moderate groups,while the MTT and TTP were higher than those in the mild and moderate groups(P<0.05);The CBF and CBV in the moderate group were lower than those in the mild group,while the MTT and TTP were higher than those in the mild group(P<0.05).The CBF and CBV in the good group were higher than those in the poor group,while the MTT and TTP were lower than those in the poor group(P<0.05).Receiver operating characteristic(ROC)curve analysis showed that the sensitivity of CBF,CBV,MTT,and TTP in predicting poor collateral circulation was 0.820,0.672,0.803,and 0.820,respectively;The specificity was 0.854,0.756,0.732,and 0.780,respectively.Conclusion CTPI scanning parameters have certain values to assess the intracranial collateral circulation status in patients with ischemic stroke.
