Alterations of brain mirror homotopic functional connectivity in vestibular migraine patients:a resting-state functional MRI study
10.3969/j.issn.1002-1671.2025.03.002
- VernacularTitle:前庭性偏头痛患者脑镜像同伦功能连接的静息态功能MRI研究
- Author:
Qifang FENG
1
;
Wen CHEN
;
Xing XIONG
;
Hongru ZHAO
;
Jun KE
;
Minmin JIN
;
Chunhong HU
Author Information
1. 苏州大学附属第一医院放射科,江苏 苏州 215006
- Publication Type:Journal Article
- Keywords:
vestibular migraine;
resting-state functional magnetic resonance imaging;
voxel-mirrored homotopic connectivity
- From:
Journal of Practical Radiology
2025;41(3):364-367
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the brain voxel-mirrored homotopic connectivity(VMHC)alterations in patients with ves-tibular migraine(VM)by using resting-state functional magnetic resonance imaging(rs-fMRI).Methods The rs-fMRI data of 30 VM patients(VM group)and 30 healthy volunteers(control group)were prospectively collected.The brain VMHC values in all subjects were calculated and the differences between the two groups were compared.The correlations between VMHC values of significant brain regions and clinical scale scores were analyzed in the VM group.Results Compared with the control group,the VMHC values of the cerebellum region 6,orbital inferior frontal gyrus,insula,superior temporal gyrus and postcentral gyrus in the VM group were all decreased[cluster-level family wise error(FWE)corrected,Pvoxel-level<0.001,Pcluster-level<0.05].In the VM group,the VMHC values of the postcentral gyrus were negatively correlated with dizziness handicap inventory(DHI)score(r=-0.383,P=0.037).Additionally,the VMHC values of the insula were negatively correlated with headache impact test-6(HIT-6)score(r=-0.430,P=0.018).Conclusion VM patients have altered VMHC in certain brain regions,indicating related dysfunctions in vestibule,pain,hearing and emotion.
