Atrioventricular block related to azithromycin
10.3760/cma.j.issn.1008-5734.2014.03.015
- VernacularTitle:阿奇霉素相关房室传导阻滞
- Author:
Ying LI
1
;
Zheng XU
;
Haiying ZHANG
;
Wanyu FENG
;
Pihua GONG
Author Information
1. 100044 北京大学人民医院药剂科; 北京大学药学院
- Publication Type:Journal Article
- Keywords:
Azithromycin;
Atrioventricular block
- From:
Adverse Drug Reactions Journal
2014;(3):176-177
- CountryChina
- Language:Chinese
-
Abstract:
An 86-year-old female patient with pulmonary infection was treated with IV infusions of ceftriaxone sodium 2. 0 g once daily,azithromycin 0. 5 g once daily,and ambroxol hydrochloride 30 mg twice daily. About 30 minutes after the fourth infusion of azithromycin,the patient abruptly developed chest tightness and suffocation. Electrocardiography showed Ⅲ degree atrioventricular block. Azithromycin was stopped immediately and she was treated with oxygen inhalation. One hour later,the symptoms of chest tightness and suffocation disappeared. Five hours later,a repeat electrocardiography showed sinus rhythm. Azithromycin was not given again and the similar symptoms did not recur any more.
