Analysis of prognostic factors in children of intraocular retinoblastoma with monocular disease-based on MRI
10.3969/j.issn.1002-1671.2025.03.024
- VernacularTitle:基于MRI对单眼发病眼内期视网膜母细胞瘤患儿预后因素分析
- Author:
Lin LI
1
;
Chongyang XU
;
Chunhua DONG
Author Information
1. 山东大学附属儿童医院医学影像科,山东 济南 250022
- Publication Type:Journal Article
- Keywords:
magnetic resonance imaging;
intraocular;
monocular;
retinoblastoma;
prognosis
- From:
Journal of Practical Radiology
2025;41(3):467-470
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relevant prognostic factors of retinoblastoma(RB)in children after selective ophthalmic artery infusion(SOAI).Methods The MRI and clinical data of 256 children with intraocular RB in monocular disease were analyzed retro-spectively.The influence of various factors on the prognosis was analyzed.Results Chidren with higher signal intensity(△SI),lon-ger distance from optic disc,smaller tumor diameter,no implant focus or small implant area,endogenous growth pattern,smaller retinal exfoliation area,no clinical risk factors,no vitreous hemorrhage,no eyeball shrinkage had better prognoses(P<0.05),the distance between tumor and optic disc,clinical risk factors and tumor growth pattern were independent prognostic factors.Conclusion The distance between tumor and optic disc,clinical risk factors and tumor growth pattern are closely related to the prognosis of children.Other factors can be used as important indicators to evaluate the prognosis of children.
