Comparative study of three-dimensional pseudo-continuous arterial spin labeling and diffusion weighted imaging in the differential diagnosis of stage T1 nasopharyngeal carcinoma and lymphoid hyperplasia
10.3969/j.issn.1002-1671.2025.03.007
- VernacularTitle:三维准连续式动脉自旋标记与扩散加权成像在鉴别T1期鼻咽癌及淋巴组织增生的对照研究
- Author:
Wenjuan ZHOU
1
;
Zhiying MO
1
Author Information
1. 梧州市人民医院放射科,广西 梧州 543000
- Publication Type:Journal Article
- Keywords:
three-dimensional pseudo-continuous arterial spin labeling;
diffusion weighted imaging;
nasopharyngeal carcinoma;
lymphoid hyperplasia
- From:
Journal of Practical Radiology
2025;41(3):385-389
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of three-dimensional pseudo-continuous arterial spin labeling(3D pCASL)and diffu-sion weighted imaging(DWI)in the differential diagnosis of stage T1 nasopharyngeal carcinoma(NPCT1)and lymphoid hyperplasia(LH).Methods A total of 21 patients with pathological diagnosis and clinical stage of NPCT1(NPCT1 group)and 50 patients with pathological diagnosis of LH(LH group)were selected.All patients underwent nasopharyngeal 3D pCASL and DWI scans before treatment.The blood flow(BF)values of all lesions[minimum BF(BFmin),mean BF(BFmean),maximum BF(BFmax)],and the rel-ative blood flow(rBF)values of the ratio of lesions to lateral pterygoid muscle at the same plane[minimum rBF(rBFmin),mean rBF(rBFmean),maximum rBF(rBFmax)],the apparent diffusion coefficient(ADC)values[minimum ADC(ADCmin),mean ADC(ADCmean),maximum ADC(ADCmax)]of all lesions were measured.The differences in parameters between NPCT1 group and LH group were analyzed,and the diagnostic efficiency of each parameter was analyzed via receiver operating characteristic(ROC)curve.Results The values of BFmean,BFmax,rBFmin,rBFmean and rBFmax of NPCT1 group were higher than those of LH group,with statisti-cally significant difference(P<0.05).However,there were no significant difference in the values of ADCmin,ADCmean and ADCmax between the two groups(P>0.05).The area under the curve(AUC)of BFmean,BFmax,rBFmin,rBFmean and rBFmax values for differen-tial diagnosis of NPCT1 and LH were 0.677,0.804,0.748,0.746 and 0.858,respectively.Conclusion 3D pCASL technique can reflect non-invasively the difference of blood perfusion between NPCT1 and LH,and can be used as an effective method to distin-guish NPCT1 from LH,with the better diagnostic efficiency of BFmax and rBFmax.However,DWI is difficult to distinguish the difference of water molecule diffusion between NPCT1 and LH,which has limited value in differential diagnosis.
