Diagnostic value of endoscopic ultrasound-guided fine needle aspiration for biopsy-negative esophageal strictures
- VernacularTitle:超声内镜引导细针穿刺抽吸术在常规内镜活检阴性食管狭窄病变中的诊断价值
- Author:
Mireayi NUERMAIMAITI
1
;
Dehua TANG
1
;
Congqiang SHEN
1
;
Xinyu TIAN
1
;
Yuhang ZHUANG
1
;
Shanshan SHEN
1
;
Chunyan PENG
1
;
Lei WANG
1
;
Shu ZHANG
1
;
Ying LYU
1
Author Information
- Publication Type:Journal Article
- Keywords: Esophageal stenosis; Biopsy negative; Endoscopic ultrasound-guided fine needle aspiration
- From: Chinese Journal of Digestive Endoscopy 2025;42(1):60-65
- CountryChina
- Language:Chinese
- Abstract: Objective:To investigate the diagnostic value of endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) for biopsy-negative esophageal strictures suspected for malignancy.Methods:Patients who underwent EUS-FNA for esophageal strictures with negative endoscopic biopsies in Nanjing Drum Tower Hospital from January 2014 to March 2022 were analyzed retrospectively. The final diagnosis was based on the pathological outcomes of EUS-FNA or surgery, complemented by follow-up data. Diagnostic efficacy and complication rates of EUS-FNA were analyzed.Results:A total of 64 patients were included in this study,with 54 ultimately diagnosed with malignant lesions and 10 with benign lesions. Malignant lesions were diagnosed by EUS-FNA in 50 cases, suspected malignant lesions in 3 cases, and no clear basis for malignancy was observed in 11 cases. The diagnostic accuracy of EUS-FNA was 98.4% (63/64), with the malignant tumor detection rate of 98.1% (53/54). No post-procedure complications such as bleeding, perforation, or infection were observed in any patient.Conclusion:EUS-FNA is safe and effective for the diagnosis of biopsy-negative suspected malignant esophageal stricture with a high malignant lesion detection rate.
