Severe bronchial asthma induced by compound codeine phosphate and ibuprofen sustained release tablets
10.3760/cma.j.issn.1008-5734.2015.04.011
- VernacularTitle:洛芬待因缓释片诱发重度支气管哮喘发作
- Author:
Xiaolan ZHANG
1
;
Peng ZHAO
;
Guoxian MA
;
Jiayi GAO
Author Information
1. 首都医科大学附属潞河医院药剂科, 北京,101149
- Publication Type:Journal Article
- Keywords:
Asthma;
Compound codeine phosphate and ibuprofen sustained release tablets
- From:
Adverse Drug Reactions Journal
2015;(4):296-297
- CountryChina
- Language:Chinese
-
Abstract:
A 68-year-old female patient with multiple fractures of the right distal radius received oral compound codeine phosphate and ibuprofen sustained release tablets(containing ibuprofen 0. 2 g,codeine phosphate 13 mg per tablet)3 tablets twice daily after plaster external fixation. Ten minutes after the first administration,the patient developed wheezing,palpitation,pale,cough,expectoration,nausea,and vomiting. Oxygen inhalation,IV infusion of doxofylline and methylprednisolone sodium succinate for injection,and terbutaline sulphate solution for nebulization and budesonide suspension for inhalation were given immediately. Two hours after treatments,wheezing was relieved and wheezing rales in the lung disappeared. By asking the medical history,it was found that the patient had developed wheezing after taking somedon and was diagnosed as bronchial asthma 1 month ago in another hospital.
