Autoimmune progesterone dermatitis induced by dydrogesterone
- VernacularTitle:地屈孕酮致自身免疫性黄体酮皮炎
- Author:
Fang KONG
1
;
Yi ZHAO
1
;
Qiuju LIAO
1
;
Li SU
1
;
Xu HUANG
1
;
Naichang YU
1
;
Xiaoxia LI
1
Author Information
- Publication Type:Journal Article
- Keywords: Dydrogesterone; Autoimmune progesterone dermatitis
- From: Adverse Drug Reactions Journal 2015;(4):297-298
- CountryChina
- Language:Chinese
- Abstract: A 41-year-old woman with systemic lupus erythematosus ( SLE ) took 10 mg dydrogesterone orally twice daily for 7 days for endometrial hyperplasia. Four days after dydrogesterone administration,she developed red maculopapule on her face. She took dydrogesterone at the same dosage for 14 days for second month and developed more severe rashes and generalized exanthematous pustulosis. Active SLE,infections,intoxication or tumors were excluded by lab examinations and SLE disease activity index scores and autoimmune progesterone dermatitis induced by dydrogesterone was diagnosed. Dydrogesterone was stopped and antianaphylaxis treatment was given. Two months later,her symptoms improved gradually and no skin rash was found at 3-month follow-up.
