Postoperative delirium and blurry vision in children associated with penehyclidine and scopolamine
10.3760/cma.j.issn.1008-5734.2015.04.019
- VernacularTitle:戊乙奎醚与东莨菪碱联用致儿童术后视物模糊及谵妄
- Author:
Jianshe WANG
1
;
Jian FEI
1
;
Xifeng ZHANG
1
Author Information
1. 南京医科大学附属南京儿童医院麻醉科, 南京,210008
- Publication Type:Journal Article
- Keywords:
Penehyclidine;
Scopolamine;
Delirium
- From:
Adverse Drug Reactions Journal
2015;(4):309-310
- CountryChina
- Language:Chinese
-
Abstract:
An 8-year-old girl was scheduled to undergo appendectomy for acute appendicitis. Preoperative conditions were normal. Scopolamine 0. 2 mg was intramuscularly injected 30 min preopera-tively. Anesthesia was induced by penehyclidine hydrochloride(0. 3 mg),midazolam(1. 0 mg),fentanyl (80 μg),propofol(80 mg)and rocuronium(25 mg),and propofol(6-8 mg·kg-1 ·h-1 )and remifentanil (0. 2-0. 5 μg · kg-1 · min-1 )for maintenance. Surgery went smoothly and safely. After three hours,the patient complained of blurred vision,and delirium. Bilateral pupils enlarged as compared with that of normal age,light reflex was normal. Ophthalmological consultation considered it as anticholinergic drug-induced mydriasis,with no special treatment. About 15 h postoperatively delirium disappeared and about 50 h postoperative blurred vision disappeared.
