Digoxin excessiving resulted atrial fibrillation with Ⅲ degree atrioventricular block
10.3760/cma.j.issn.1008-5734.2015.04.024
- VernacularTitle:地高辛过量致心房颤动伴Ⅲ度房室传导阻滞
- Author:
Yi LI
1
;
Fenghua YIN
;
Bei LAI
Author Information
1. 162850,内蒙古自治区呼伦贝尔市莫力达瓦达斡尔族自治旗人民医院心内科
- Publication Type:Journal Article
- Keywords:
Digoxin;
Atrial fibrillation;
Atrioventricular block
- From:
Adverse Drug Reactions Journal
2015;(4):318-319
- CountryChina
- Language:Chinese
-
Abstract:
A 72-years-old woman mistook digoxin 40 tablets(10 mg)within 7 days for chronic cardiac insufficiency. She developed nausea, vomiting, blurred vision, xanthopsia, chloropsia and dizziness. After admission,her heart rate was 38 beats/ min and blood pressure was 135 / 75 mmHg. Electrocardiogram revealed atrial fibrillation with 3rd degree atrioventricular block. Digitalis poisoning was diagnosed. She was given oral theophylline 200 mg,intramuscular injection of 10 mg anisodamine. After 2. 5 hours,the heart rate did not significantly change. She was given intramuscular injection of atropine 0. 5 mg, intravenous infusion of atropine 0. 5 mg and 1. 0 mg once every 0. 5 hour. Her heart rate continued to decline,the lowest heart rate was 19 beats/ min,and developed unconsciousness and hallucination. She received isoprenaline 1 mg by a continuous infusion pump delivering 0. 5 μg per minute. The heart rate was maintained at about 40 beats/ min. On day 2,the patient regained consciousness. Electrocardiogram showed atrial fibrillation with ventricular bigeminy. Isoprenaline was stopped and ventricular bigeminy disappeared. Her heart rate was 38 times/ min. On day 5,the blurred vision,xanthopsia and chloropsia disappeared. On day 6,the nausea and vomiting disappeared. On day 8,the electrocardiogram revealed atrial fibrillation with a heart rate of 54 beats/ min.
