Blurred vision induced by acyclovir
10.3760/cma.j.issn.1008-5734.2016.04.023
- VernacularTitle:阿昔洛韦致视物模糊
- Author:
Qushen SHEN
1
;
Chibang CHEN
;
Yongheng ZHOU
;
Nanxing PENG
;
Chunxia LIU
Author Information
1. 511300,广州市增城区人民医院/中山大学附属博济医院药剂科
- Publication Type:Journal Article
- Keywords:
Acyclovir;
Vision disorders
- From:
Adverse Drug Reactions Journal
2016;18(4):314-316
- CountryChina
- Language:Chinese
-
Abstract:
A 24-year-old male patient with viral meningoencephalitis received intravenous infusion of acyclovir 0.5 g thrice daily,Xingnaojing injection（醒脑静注射液）20 ml once daily,mannitol injection 250 ml thrice daily,creatine phosphate sodium 1 g once daily,insulin injection (6 U + 5 ％ glucose injection 500 ml+potassium chloride injection 10 ml),Xueshuantong injection（血栓通注射液）500 mg once daily,mecobalamin injection 2 rnl once daily,and oral butylphthalide soft capsules 0.2 g thrice daily,ranitidine bismuth citrate capsules 0.2 g twice daily,etc.On day 7,the patient developed visual blurring and could not see distant objects clearly.At the same time,the patient experienced mydriasis with diameter about 5.0 mm and conjunctival congestion.Acyclovir was discontinued and other drugs were continued.Five days after withdrawal,his symptoms of conjunctival congestion,mydriasis,and vision were improved.At 2 months of follow-up,blurred vision did not recur.
