Shared genetic basis between obsessive-compulsive disorder and other major mental disorders: a review of updated research
10.3760/cma.j.cn113661-20210329-00126
- VernacularTitle:强迫症与其他重性精神障碍共同遗传基础研究的最新进展
- Author:
Miaohan DENG
1
;
Yuan WANG
1
;
Zeping XIAO
1
Author Information
1. 上海交通大学医学院附属精神卫生中心 200030
- Publication Type:Journal Article
- Keywords:
Obsessive-compulsive disorder;
Bipolar disorder;
Autistic disorder;
Schizophrenia;
Genetics
- From:
Chinese Journal of Psychiatry
2021;54(6):421-427
- CountryChina
- Language:Chinese
-
Abstract:
The comorbidity of obsessive-compulsive disorder and other severe mental illnesses is common in clinical practice, which indicates a possible common genetic basis of them. Studies on this common genetic basis can be helpful for directing the clinical treatment strategy and further understanding the etiology and pathogenesis of obsessive-compulsive disorder and its comorbidity of other severe mental illnesses. This study summarized the updated research about the shared genetic basis between obsessive-compulsive disorder and other severe mental illnesses, to provide a possible direction for the exploration of pathogenesis and mechanism of the diseases and the formulation of treatment strategies.
