Characteristics and mechanism of error-related negativity in patients with obsessive-compulsive disorder
10.3760/cma.j.cn113661-20210131-00062
- VernacularTitle:强迫症患者错误相关负波特征及机制研究进展
- Author:
Wenwen CAO
1
;
Pengchong WANG
1
;
Xiangyun YANG
1
;
Zhanjiang LI
1
Author Information
1. 首都医科大学附属北京安定医院 国家精神心理疾病临床医学研究中心 精神疾病诊断与治疗北京市重点实验室 100088
- Publication Type:Journal Article
- Keywords:
Obsessive-compulsive disorder;
Error-related negativity;
Performance monitoring;
Endophenotype
- From:
Chinese Journal of Psychiatry
2021;54(6):409-414
- CountryChina
- Language:Chinese
-
Abstract:
The error-related negativity (ERN) is the medical frontal lobe component of event-related potentials caused by the individual incorrect response. It is an important indicator that reflects the function of performance monitoring. This article reviewed the characteristics and influencing factors of ERN in patients with obsessive-compulsive disorder (OCD), and also discussed the relationship between ERN and the clinical symptoms of OCD, the changes of ERN during treatment, the underlying neurological basis, and the possibility of ERN as an endophenotype of the disorder, thereby providing a new perspective on understanding the pathological mechanisms of OCD.
