Research progress of placebo effect in depression research
10.3760/cma.j.cn113661-20201013-00437
- VernacularTitle:抑郁症研究中安慰剂效应的研究进展
- Author:
Jiali HAN
1
;
Xuequan ZHU
1
;
Lei FENG
1
;
Gang WANG
1
Author Information
1. 首都医科大学附属北京安定医院 国家精神心理疾病临床医学研究中心 精神疾病诊断与治疗北京市重点实验室 首都医科大学人脑保护高精尖创新中心100088
- Publication Type:Journal Article
- Keywords:
Depression disorder;
Antidepressive agents;
Placebo effect;
Psychological mechanism;
Neurological mechanism
- From:
Chinese Journal of Psychiatry
2021;54(5):396-400
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, findings from various randomized, double-blind, placebo-controlled trials of antidepressants have showed that the efficacy of drug treatment is not significantly different from that of placebo, therefore, scholars have begun to pay attention to the influence of placebo in it. In the research field of major depressive disorder, the mechanism and control measures for the placebo effect are still being explored. This article introduces the origins of placebo and placebo effects, and summarizes recent research results related to the psychological and neurological mechanisms of placebo effects. Additionally, we discuss the methods of controlling placebo effects in clinical drug trials, and provide references for future placebo-controlled trials.
