Advancements and frontiers in targeted therapy for pancreatic cancer
10.12092/j.issn.1009-2501.2025.02.004
- VernacularTitle:胰腺癌的靶向治疗进展及前沿
- Author:
Nan DU
1
;
Miaoyan WEI
1
;
Jin XU
1
Author Information
1. 复旦大学附属肿瘤医院胰腺外科,复旦大学上海医学院肿瘤学系,上海市胰腺肿瘤研究所,上海市胰腺肿瘤精准诊疗重点实验室,复旦大学胰腺肿瘤研究所,上海 200032
- Publication Type:Journal Article
- Keywords:
pancreatic cancer;
targeted therapy;
chemotherapy
- From:
Chinese Journal of Clinical Pharmacology and Therapeutics
2025;30(2):183-192
- CountryChina
- Language:Chinese
-
Abstract:
The incidence of pancreatic cancer has been increasing each year,and the 5-year survival rate is still around 10%.Diagnosis and treatment strategies are major concerns in the industry.Gene sequencing and multi-omics research have revealed more signal pathways and actionable targets,offer-ing the potential for new targeted therapeutic drugs.However,current drug treatment for pancre-atic cancer still relies mainly on chemotherapy,and targeted therapy strategies are not yet fully devel-oped and require further discussion.As basic and translational research in pancreatic cancer advances and precision medicine develops,it is expected that targeted treatment for pancreatic cancer will be-come more precise and individualized in the future.This article discusses the current progress and fron-tiers of targeted treatment for pancreatic cancer.