A follow-up controlled study of repeated cue exposure therapy combined with biofeedback training for patients with alcohol dependence after the acute withdrawal
10.3760/cma.j.cn113661-20200522-00235
- VernacularTitle:反复线索暴露治疗联合生物反馈训练治疗急性脱瘾后酒依赖患者的随访对照研究
- Author:
Jun WANG
1
;
Kebing YANG
1
;
Zhaoxia ZHAO
1
;
Rongjiang ZHAO
1
;
Jian CUI
1
;
Na HU
1
;
Ying NIE
1
;
Qingyan YANG
1
;
Jing GAO
1
;
Yajuan NIU
1
Author Information
1. 北京回龙观医院 100096
- Publication Type:Journal Article
- Keywords:
Behavior, Addictive;
Alcohol dependence;
Repeated cue exposure;
Recurrence;
Biofeedback, psychology
- From:
Chinese Journal of Psychiatry
2021;54(1):31-37
- CountryChina
- Language:Chinese
-
Abstract:
Objective:This study aims to investigate the effect of repeated cue exposure therapy combined with biofeedback training on patients with alcohol dependence after acute withdrawal.Methods:A total of 130 male alcohol dependent patients (PADs) who were hospitalized in Beijing Huilongguan Hospital from November 2016 to June 2018 were enrolled, and after the alcohol withdrawal syndrome eliminated, the PADs were divided into two groups by randomized controlled research methods as follows: repeated cue exposure combined biofeedback therapy group (study group, SG) and routine treatment group (control group, CG). After controlling the symptoms of acute alcohol withdrawal, the SG patients were given cue exposure therapy and biofeedback training 12 times, and the CG patients were given routine rehabilitation treatment and general psychological support over a four-week session. The psychological craving for alcohol of two groups were evaluated with Visual Analog Scale (VAS) and Alcohol Urge Questionnaire (AUQ) before and afer treatment. Both groups were discharged after four-week treatment and received follow-ups at the end of the 4th, 8th, 12th, 24th and 52th week, respectively. The alcohol consumption questionnaire was used to evaluated with the recurrence rate, cumulative abstinence duration (CAD), time to first re-drinking, and average daily alcohol consumption after relapse for each follow-up assessment. Independent sample t test or chi-square test was used for comparison between groups. Results:The decrement of VAS before and after cue exposure treatments in the SG was significantly higher than that in the CG (2.10(0.33,2.78) vs. 0.60(-0.30,1.70), Z=-3.50, P=0.001).The decrement of AUQ score was also significantly higher than the CG (3.00(1.00,6.00) vs.1.00(-2.00,4.00), Z=-3.02, P=0.003). There was a significant difference in the rate of recurrence at the end of week-4 between the SG and CG (30.0% vs. 54.2%, χ2=7.17, P=0.007). The time before the first re-drinking in the experimental group was longer than that in the control group (52.5(26.0,208.5) d vs. 21.0(5.0,183.0) d, Z=-2.5, P=0.013). The total average daily alcohol consumption of the experimental group was lower than that of the Control Group (11.0±8.5 vs.15.2±8.6, t=-2.69, P=0.008). Conclusions:The results suggest that repeated cue exposure combined with biofeedback therapy can reduce the psychological craving for alcohol and recurrence rate after a short term of treatment. Meanwhile, the long-term (follow-up 1 year after treatment) recurrence rate may not change significantly, however the first re-drinking can be postponed, and they tend to drink less even if they re-drink again.
