Supraventricular tachycardia in a child induced by intravenous infusion of azithromycin
10.3760/cma.j.issn.1008-5734.2014.02.021
- VernacularTitle:静脉滴注阿奇霉素致儿童室上性心动过速
- Author:
Jie GAO
1
;
Yongfu HANG
1
;
Cheng XIE
1
;
Xiaoxian ZHENG
1
Author Information
1. 215006,苏州大学附属第一医院药学部
- Publication Type:Journal Article
- Keywords:
Azithromycin;
Supraventricular tachycardia;
Children
- From:
Adverse Drug Reactions Journal
2014;16(2):125-126
- CountryChina
- Language:Chinese
-
Abstract:
A 13-year-old boy (weighing 24 kg) after allogeneic transplantation due to acute lymphoblastic leukemia received an Ⅳ infusion of azithromycin at a dose of 20.8 mg/kg because of pneumonia.At the end of intravenous infusion of azithromycin for the first time,the boy developed palpitation and the heart rate was 225 beats/min,blood pressure 75/45 mmHg,and oxygen saturation 0.98.The ECG examination showed supraventricular tachycardia and narrow QRS complex.The bedside echocardiographic examination showed a small amount of pericardial effusion,slight decrease of the motion range of left ventricular posterior wall,and ejection fraction 0.58.Azithromycin was discontinued immediately and his carotid sinus and eyeball were pressed alternately.About 10 minutes later,his heart rate dropped to 120 beats/min,sinus rhythm recovered,and blood pressure was 92/62 mmHg.Two days later,his ECG examination showed normal and his heart rate was 87 beats/min.
