Effect of virtual reality attention training on cognitive function in patients with depressive episodes
10.3760/cma.j.cn113661-20191009-00348
- VernacularTitle:基于虚拟现实注意力训练对抑郁发作患者认知功能干预的研究
- Author:
Sihui LYU
1
;
Lu ZHANG
;
Shuming ZHONG
;
Yanbin JIA
;
Shunkai LAI
;
Shiyi SHEN
;
Yanyan SHAN
;
Xuanjun LIU
;
Yilei HU
;
Haofei MIAO
Author Information
1. 暨南大学附属第一医院精神医学科，广州 510632
- Publication Type:Journal Article
- Keywords:
Depressive disorder;
Depression;
Virtual reality;
Attention;
Cognition
- From:
Chinese Journal of Psychiatry
2020;53(5):384-391
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect of virtual reality (VR) attention training on cognitive function in patients with depressive episode.Methods:64 patients diagnosed as major depressive disorder and bipolar disorder depressive episodes according to the DSM-5 criteria were recruited. They were randomized into virtual reality training (VRT) group ( n=23), computerized cognitive remediation therapy (CCRT) group ( n=21) and blank control group ( n=20). Prior to the intervention, seven cognitive functions were assessed with the MATRICS Consensus Cognitive Battery (MCCB)-B version in all patients, via information processing speed (IPS), attention/alertness (ATT), working memory, word learning, visual learning (VL), reasoning and problem solving, and social cognition. VRT group and CCRT group were trained for four weeks at a frequency of five days a week, and half an hour for each day training. Blank control group did not receive any treatment related to attention training. After the training, three groups were assessed by the MCCB-A. The differences of the cognitive functions among three groups were explored by the repeated analysis of ANOVA and paired sample ttest. Results:(1) Before the intervention, there were no differences in all cognitive functions (all P>0.05) among three groups. (2) After four-week interventions, the cognition of IPS, ATT and VL in VRT group (56.74±9.68, 56.48±10.22, 57.83±4.16), CCRT group (48.90±9.77, 49.48±9.51, 55.95±5.52) and the blank control group (50.35±7.93, 47.55±7.80, 47.95±9.90) had significant groups×time interactions ( F=14.06, 12.88, 9.39, all P<0.01); simple effect analysis showed that IPS and ATT scores in VRT group were higher than both CCRT group and the blank control group (all P<0.05), while the VL scores in VRT group and CCRT group were both higher than the blank control group (all P<0.01).(3) Cognitive functions in VRT group significantly improved in IPS, ATT, VL and overall domains compared with the baseline ( t=-9.33, -6.00, -5.13, -6.26, all P<0.01). Conclusion:VR attention training may be more beneficial than CCRT attention training to improve the attention among depressive patients.
