Research progress on neuropathophysiological mechanism of patients with type 2 diabetes comorbid depression
10.3760/cma.j.cn113661-20190626-00212
- VernacularTitle:2型糖尿病共病抑郁的神经病理生理机制研究进展
- Author:
Yashan LU
1
;
Gang HUANG
;
Lianping ZHAO
Author Information
1. 甘肃中医药大学临床医学院,兰州 730000
- Publication Type:Journal Article
- Keywords:
Diabetes Mellitus;
Depression
- From:
Chinese Journal of Psychiatry
2020;53(3):263-266
- CountryChina
- Language:Chinese
-
Abstract:
Type 2 diabetes often comorbid with depression (T2DD),leading to poor compliance,poor self-management and increasing social burden.However,the underlying pathophysiological mechanism has not been fully elucidated.Numerous studies mainly focused on the hypothalamic-pituitary-adrenalaxis,immune inflammatory system,insulin resistance and neuroimaging changes of T2DD.Thus the present review will summarize the major recent advances in current understanding of T2DD.