Effect of exercise on freezing of gait in Parkinson's disease:a meta-analysis
10.3969/j.issn.1006-9771.2025.07.005
- VernacularTitle:运动干预对帕金森病冻结步态效果的Meta分析
- Author:
Wenqian DU
1
;
Xu ZHANG
1
;
Jiwei CHEN
1
;
Xing WANG
1
;
Kun ZHU
1
Author Information
1. 上海体育大学体育教育学院,上海市 200438
- Publication Type:Journal Article
- Keywords:
Parkinson's disease;
exercise;
freezing of gait;
meta-analysis
- From:
Chinese Journal of Rehabilitation Theory and Practice
2025;31(7):781-789
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of exercise on freezing of gait in Parkinson's disease.Methods After constructing a PICO framework,randomized controlled trials(RCTs)about exercise for freezing of gait in Parkinson's disease were systematically retrieved from Web of Science,PubMed,Cochrane Library,Embase,CNKI,VIP and Wanfang Data,from the establishment of the databases to March,2025.The PEDro scale was used to evaluate the quality of literature,Stata 17.0 was used for meta-analysis,and GRADE was used to assess the evidence quality.Results A total of twelve RCTs involving 463 patients were included,with PEDro scale scores of five to eight.Exercise improved the scores of Freezing of Gait Questionnaire(FOGQ)(SMD=-0.61,95%CI-0.85～-0.36,P<0.001)and Unified Parkinson's Disease Rating Scale Ⅲ(UPDRSⅢ)(SMD=-0.84,95%CI-1.27～-0.41,P<0.001).Subgroup analysis revealed that the patients aged 59 to 68 years,the course of disease
