Subcutaneous hemorrhage induced by Zhisou Lixiao Wan in patient who used warfarin for long-term
10.3760/cma.j.issn.1008-5734.2017.03.015
- VernacularTitle:止嗽立效丸致长期服用华法林患者皮下出血
- Author:
Wenjun YU
1
;
Cuiting QIU
;
Nan SHEN
;
Quanchu ZHANG
;
Na LI
Author Information
1. 解放军第三〇六医院急诊部, 北京,100101
- Publication Type:Journal Article
- Keywords:
Warfarin;
Hemorrhage;
Zhisou Lixiao Wan
- From:
Adverse Drug Reactions Journal
2017;19(3):222-223
- CountryChina
- Language:Chinese
-
Abstract:
A 68-year-old female patient with rheumatic heart disease and auricular fibrillation received warfarin (10.5 mg per week, totally 6 weeks;then 12 mg per week, totally 3 weeks).The international nomalized ratio (INR) was monitored regularly.Her INR was steady and reached the standard during the medication.She took Zhisou Lixiao Wan 12 g daily by herself because of cough on the 10th week.Four days later she found multiple ecchymosis at her front of right leg and the INR was 6.46.Warfarin was withdrawn while Zhisou Lixiao Wan was continued.Three days later, the ecchymosis was absorbed obviously and the INR decreased to 2.96.Zhisou Lixiao Wan was stopped and warfarin was taken by 12 mg weekly.Five days later, her INR was 2.24 and the ecchymosis disappeared completely.
