Neutropenia induced by meropenem in a newborn
10.3760/cma.j.issn.1008-5734.2017.03.017
- VernacularTitle:美罗培南致新生儿中性粒细胞减少
- Author:
Xiaojing HUANG
1
;
Naijun GAO
;
Lin HUANG
;
Qun GU
;
Wanyu FENG
Author Information
1. 河南省人民医院药学部, 郑州,450003
- Publication Type:Journal Article
- Keywords:
Neutropenia;
Infant;
newborn;
Meropenem
- From:
Adverse Drug Reactions Journal
2017;19(3):226-227
- CountryChina
- Language:Chinese
-
Abstract:
A 19-day-old female neonate was treated with an IV infusion of meropenem 26 mg every 8 hours for neonatal clinical sepsis.Before the treatment, the newborn's neutrophil count (NEUT) was 1.0×109/L.On day 3 of administration of meropenem, the NEUT was 1.0×109/L.On day 4, meropenem dosage was increased to 52 mg every 8 hours to strengthen the anti-infective therapy.On day 8, the NEUT was 0.9×109/L.On day 16, the NEUT declined to 0.3×109/L.On day 20, her infection was under control, and meropenem was withdrawn.The results of reexamination 3 days later showed NEUT 3.3×109/L.
