Thrombocytopenia caused by cefpiramide in a child
10.3760/cma.j.issn.1008-5734.2017.03.019
- VernacularTitle:头孢匹胺致患儿血小板减少
- Author:
Haiyan LIU
1
;
Tingting LI
;
Linhai HE
;
Guoyun LI
Author Information
1. 西双版纳傣族自治州人民医院临床药学科, 云南省景洪市,666100
- Publication Type:Journal Article
- Keywords:
Cefpiramide;
Thrombocytopenia
- From:
Adverse Drug Reactions Journal
2017;19(3):230-232
- CountryChina
- Language:Chinese
-
Abstract:
An 8-year-old boy with acute appendicitis received an IV infusion of cefpiramide 1 g twice daily.Before treatment, the patient's PLT was 296×109/L.On the 3rd day of treatment, PLT dropped to 15×109/L, on the 4th day, PLT decreased to 1×109/L, accompanied by melena and fecal occult blood test (++++).Cefpiramide was discontinued immediately, then comprehensive treatments including transfusion of platelets, application of hemostatic agents, and supplement of vitamin K1 were given to the patient.Four days later, PLT of the patient returned to 165×109/ L.