Research progress on microcystic macular edema in glaucoma: current status
10.3760/cma.j.cn511434-20240805-00298
- VernacularTitle:微囊样黄斑水肿在青光眼中的研究进展
- Author:
Yuan LIU
1
;
Chengguo ZUO
1
;
Xing LIU
1
Author Information
1. 中山大学中山眼科中心 眼病防治全国重点实验室 广东省眼科视觉科学重点实验室, 广州 510060
- Publication Type:Journal Article
- Keywords:
Glaucoma;
Microcystic macular edema;
Optical coherence tomography;
Review
- From:
Chinese Journal of Ocular Fundus Diseases
2025;41(4):307-310
- CountryChina
- Language:Chinese
-
Abstract:
Microcystic macular edema (MME) represents a pathological change that can be observed in the inner layer of the retina in patients diagnosed with glaucoma. This phenomenon is particularly prevalent in individuals with moderate to advanced glaucoma. The majority of research in this field has focused on primary open-angle glaucoma. The occurrence of MME in glaucoma has been demonstrated to be associated with younger age, advanced stage and disease progression. MME occurs in the parafoveal region, most frequently located in the inferior perimacular region, which corresponded with the most vulnerable area of ganglion cells in glaucoma. The presence of MME may affect the automatic layering of optical coherence tomography images, suggesting that clinicians should be mindful of the occurrence of MME to avoid misdiagnosis of the disease. It is hypothesised that the occurrence of MME in glaucoma may be related to macular vitreous traction, mechanical stress of the stent, and Müller cell dysfunction. A comprehensive investigation of the precise pathophysiological mechanism of MME in glaucoma will facilitate the development of a novel perspective and a scientific foundation for the diagnosis, disease monitoring and evaluation of treatment efficacy in glaucoma.
