The clinical value of the procalcitonin-to-albumin ratio in predicting short-term prognosis in patients with acute cerebral infarction
10.3760/cma.j.cn115455-20240522-00431
- VernacularTitle:降钙素原与白蛋白比值预测急性脑梗死患者短期预后的临床价值
- Author:
Rong WANG
1
;
Shanchen JU
1
;
Xiaoling LIN
1
;
Xiaoxiao DAI
1
Author Information
1. 中国人民解放军联勤保障部队第九七〇医院神经内科，烟台 264000
- Publication Type:Journal Article
- Keywords:
Cerebral infarction;
Albumin;
Interventional surgery;
Butylphthalide;
Sequential treatment;
Procalcitonin
- From:
Chinese Journal of Postgraduates of Medicine
2025;48(1):54-59
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the predictive value of procalcitonin-to-albumin ratio (PAR) in the short-term prognosis of sequential treatment with butylphthalide for acute cerebral infarction (ACI) after interventional surgery.Methods:The clinical data of ACI patients admitted to 970th Hospital of the Joint Logistics Support Force of the People′s Liberation Army of China from January 2020 to June 2022 were retrospectively included. According to the prognosis of sequential treatment of butylphthalide after interventional therapy, 80 patients with poor prognosis were included in the poor group, and 80 patients with good prognosis were included in the good group. The detection data of procalcitonin, albumin and other laboratory indexes of the two groups of patients on admission were collected, the PAR value was calculated, and the predictive value of PAR on the short-term prognosis of butylphthalide sequential therapy after ACI intervention was analyzed.Results:The levels of procalcitonin (PCT), PAR, D-dimer (D-D), and low density lipoprotein cholesterol (LDL-C) in the poor group were higher than those in the good group: (24.74 ± 5.37) ng/L vs. (20.96 ± 4.11) ng/L, 0.91 ± 0.35 vs. 0.62 ± 0.19, (0.75 ± 0.22) mg/L vs. (0.56 ± 0.17) mg/L, (3.28 ± 0.43) mmol/L vs. (3.03 ± 0.45) mmol/L, while the levels of albumin (ALB) were lower than those in the good group: (29.43 ± 4.25) g/L vs. (33.71 ± 4.53) g/L, with a statistical significant difference ( P<0.05). Multivariate Logistic regression analysis showed that PCT, ALB, PAR, D-D, and LDL-C were all factors influencing the short-term prognosis of sequential treatment with butylphthalide after ACI intervention ( P<0.05). The results of receiver operating characteristic curve (ROC) showed that PCT, ALB, PAR, D-D and LDL-C had certain predictive value for the short-term prognosis of butylphthalide sequential therapy after ACI intervention, and PAR had the best predictive value. Conclusions:PAR is an influential factor for the sequential short-term prognosis of butylphthalide after ACI intervention, and it has certain predictive value for the short-term prognosis of patients.
