Research progress on the impact of metabolic associated fatty liver disease on viral activity, treatment response, and prognosis in patients with chronic hepatitis B: current status and prospects
10.3760/cma.j.cn501113-20240930-00515
- VernacularTitle:代谢相关脂肪性肝病对慢性乙型肝炎患者的病毒活性、治疗应答及预后影响的研究进展：现状与展望
- Author:
Huan GONG
1
;
Tingting ZHAO
1
;
Meng HUANG
1
;
Chengcheng LIU
1
;
Na HE
1
Author Information
1. 西安医学院第一附属医院消化内科，西安 710000
- Publication Type:Journal Article
- Keywords:
Fatty liver disease;
Hepatitis B virus;
Fatty liver;
Metabolic syndrome
- From:
Chinese Journal of Hepatology
2025;33(7):683-689
- CountryChina
- Language:Chinese
-
Abstract:
Chronic hepatitis B (CHB) can gradually progress to life-threatening diseases such as cirrhosis and hepatocellular carcinoma (HCC). In recent years, with the change in people's lifestyles, the incidence rate of metabolic associated fatty liver disease has been steadily increasing and the patients combined with CHB and MAFLD has significantly surged. However, the impact of MAFLD on patients with CHB in aspects of antiviral response, clinical outcomes, and others is still controversial. This article reviews research progress on the impact of MAFLD with regard to natural course and antiviral treatment response in CHB and the survival rate in combination with CHB and MAFLD so as to provide a certain theoretical reference for prevention, diagnosis, and treatment of this disease.
