Current research progress status in identifying hepatocellular ballooning degeneration in nonalcoholic steatohepatitis
10.3760/cma.j.cn501113-20240604-00284
- VernacularTitle:非酒精性脂肪性肝炎中肝细胞气球样变现状及识别研究进展
- Author:
Haoran XIE
1
;
Lai WEI
1
Author Information
1. 清华大学附属北京清华长庚医院肝胆胰中心 清华大学临床医学院，北京 102218
- Publication Type:Journal Article
- Keywords:
Non-alcoholic steatohepatitis;
Ballooning degeneration;
Liver biopsy;
Diagnosis;
Non-invasive identification
- From:
Chinese Journal of Hepatology
2025;33(11):1111-1117
- CountryChina
- Language:Chinese
-
Abstract:
Nonalcoholic steatohepatitis (NASH) is a chronic liver disease associated with metabolic syndrome, such as obesity, diabetes, and hyperlipidemia, and is a progressive form of nonalcoholic fatty liver disease with pathological features including steatosis, lobular inflammation, and hepatocyte damage (ballooning degeneration). Hepatocellular ballooning degeneration is an important pathological feature of NASH and is closely related to the prognosis of NASH patients. Accurate identification of hepatocellular ballooning degeneration is of great significance for diagnosing NASH and assessing therapeutic response. This article reviews the current status and identification methods of hepatocellular ballooning degeneration in NASH, including invasive and noninvasive.
