Analysis on risk factors of adverse events after non-sedated esophagogastroduo-denoscopy
10.3969/j.issn.1006-7795.2025.04.014
- VernacularTitle:无镇静胃镜检查后不良反应的危险因素分析
- Author:
Shuyue YANG
1
;
Sifan LIU
1
;
Xu JI
1
;
Mengran ZHAO
1
;
Zheng ZHANG
1
;
Peng LI
1
Author Information
1. 首都医科大学附属北京友谊医院消化科 消化健康全国重点实验室 国家消化系统疾病临床医学研究中心 胃肠早癌药械研发北京市重点实验室,北京 100050
- Publication Type:Journal Article
- Keywords:
esophagogastroduodenoscopy;
non-sedated;
risk factors;
adverse events;
domestic endoscopy;
Logistic regression analysis
- From:
Journal of Capital Medical University
2025;46(4):676-681
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the risk factor for adverse events(AEs)after non-sedated esophagogastroduodenoscopy(EGD).Methods The data on clinical manifestations,adverse events after non-sedated EGD and common risk factors were collected and retrospectively analyzed with statistical methods in patients who underwent non-sedated EGD from May 2018 to June 2019.These patients were divided into AEs group and non-AEs group.Results Of 2 384 patients,57.67%(1 375/2 384)presented with nausea,12.79%(305/2 384)vomiting,and 5.79%(138/2 384)presented with pharyngalgia.Multivariate Logistic regression analysis was performed.Advanced age(≥65 years old)(OR=0.683,95%CI:0.506-0.921)was protective factors for nausea after non-sedated EGD.Hypertension(OR=1.361,95%CI:1.026-1.806),overweight(OR=1.399,95%CI:1.154-1.695),obesity(OR=2.594,95%CI:1.760-3.823)and inspection duration>15 min(OR=3.107,95%CI:2.296-4.206)were independent risk factors for nausea after non-sedated EGD.Advanced age(OR=0.393,95%CI:0.221-0.699)and imported equipment(OR=0.697,95%CI:0.546-0.890)were protective factors for vomiting after non-sedated EGD.Moreover,inspection duration>15 min(OR=1.641,95%CI:1.008-2.699)was independent risk factors for vomiting after non-sedated EGD.There was no difference in success rate of non-sedated EGD between two groups(P<0.05).Conclusion Hypertension,overweight and obesity were independent risk factors for nausea after non-sedated EGD.The advanced age and imported equipment were protective factors for vomiting after non-sedated EGD.In addition,inspection duration over 15 min is a risk factor for AEs such as nausea and vomiting after nonsedative EGD.Whether AEs occurred or not is non-related to success rate of non-sedated EGD.
