Severe hypoglycemia due to misuse of insulin aspart before bedtime in an elderly patient with type 2 diabetes mellitus
10.3760/cma.j.issn.1008-5734.2019.02.015
- VernacularTitle:老年2型糖尿病患者睡前误用门冬胰岛素致严重低血糖
- Author:
Xian DU
1
;
Yinmei YE
1
;
Peihuan SUN
1
;
Jiangxia CAI
1
;
Xinchun YAN
1
Author Information
1. 新疆维吾尔自治区巴音郭楞蒙古自治州人民医院药学部,库尔勒市,841000
- Publication Type:Journal Article
- Keywords:
Insulin;
Hypoglycemia;
Medication errors
- From:
Adverse Drug Reactions Journal
2019;21(2):144-145
- CountryChina
- Language:Chinese
-
Abstract:
A 77-year-old female patient with type 2 diabetes mellitus mistakenly injected insulin aspart 16 U subcutaneously as glargine insulin before bedtime.One hour later,she developed slow response and paraphasia.Her urgent blood glucose level was 2.8 mmol/L.An Ⅳ injection of 50% glucose injection 40 ml,mask oxygen absorption,and continuous ECG monitoring were given immediately.Thirty minutes later,her blood glucose level increased to 8.4 mmol/L.The adjusted hypoglycemic regimen was subcutaneous injection of 8,10,and 8 units of insulin aspart 15 minutes before 3 meals,respectively,and glargine insulin 18 U before bedtime.Six days later,her fasting and 2-hour postprandial blood glucose levels were 7.0-8.3 mmol/L and 9.1-10.2 mmol/L,respectively.