Mental and behavioral disorders due to tigecycline
10.3760/cma.j.issn.1008-5734.2019.02.017
- VernacularTitle:替加环素致精神行为异常
- Author:
Hong CHEN
1
;
Gaoqiong YAO
1
;
Feng QIU
1
Author Information
1. 重庆医科大学附属第一医院药学部 400016
- Publication Type:Journal Article
- Keywords:
Tigecycline;
Mental disorders;
Hallucination;
Drug-related side effects and adverse reactions
- From:
Adverse Drug Reactions Journal
2019;21(2):148-149
- CountryChina
- Language:Chinese
-
Abstract:
A 77-year-old male patient received an Ⅳ infusion of tigecycline 100 mg for the acute exacerbation of chronic obstructive pulmonary disease and the flora species being sensitive to tigecycline in his antibiotic sensitivity test.About 3 hours after the infusion,the patient developed mental and behavioral abnormalities such as hallucinations and balderdash.Tigecycline was stopped the next day,and the patient's consciousness improved and he could answer questions correctly.Because of the poor control of the infection,an Ⅳ infusion of tigecycline 50 mg was given 6 days later.About 8 hours after the infusion,the patient developed mental and behavioral abnormalities such as staring at a certain place and unresponsiveness to verbal stimuli.Then tigecycline was stopped,and the patient's consciousness recovered.
