Risk factors for cardiovascular disease in patients with rheumatoid arthritis
10.3969/j.issn.1673-9701.2025.10.005
- VernacularTitle:类风湿关节炎患者并发心血管疾病的危险因素
- Author:
Yujie LI
1
;
Yanyan YAO
;
Jingwen TANG
;
Yanmin HU
;
Shenshen ZHU
;
Linlin LI
;
Zhaoke WU
Author Information
1. 郑州大学第二附属医院老年医学科,河南郑州 450003
- Publication Type:Journal Article
- Keywords:
Rheumatoid arthritis;
Cardiovascular disease;
Neutrophil;
Platelet;
High density lipoprotein
- From:
China Modern Doctor
2025;63(10):20-24
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the risk factors for cardiovascular disease(CVD)in patients with rheumatoid arthritis(RA).Methods Clinical data of 225 patients with RA admitted to the Second Affiliated Hospital of Zhengzhou University from January 2023 to September 2024 were collected,and the patients were divided into CVD group(n=50)and non-CVD group(n=175)according to whether they were complicated by CVD.Univariate and multivariate Logistic regression was used to analyze the risk factors of CVD in RA patients.Results Univariate Logistic regression analysis showed that age,hematocrit,red cell volume distribution width(RDW),erythrocyte sedimentation rate,neutrophil to high density lipoprotein ratio(NHR)and platelet to lymphocyte ratio(PLR)were all influencing factors for CVD in RA patients(P＜0.05).Multivariate Logistic regression analysis showed that age,RDW,NHR and PLR were all risk factors for CVD in RA patients(P＜0.05).The results of receiver operating characteristic curve analysis showed that the area under the curve(AUC)of age,RDW,NHR and PLR diagnosed CVD in RA patients were 0.844,0.797,0.572 and 0.713,respectively.The combined diagnosis AUC of four indexes was 0.898.Conclusion The risk of CVD in RA patients is influenced by many factors,and the combination of age,RDW,NHR,and PLR can improve early diagnosis of CVD in RA patients.
