Comparison of the diagnostic efficacy of two transrectal ultrasound-guided puncture methods for suspected prostate cancer
10.12354/j.issn.1000-8179.2025.20241523
- VernacularTitle:两种经直肠超声引导下穿刺方法对可疑前列腺癌的诊断效能比较
- Author:
Zhang YU
1
;
Wang YING
1
Author Information
1. 上海市奉贤区中心医院超声科(上海市 201400)
- Publication Type:Journal Article
- Keywords:
prostate cancer(PCa);
contrast-enhanced ultrasonography(CEUS);
targeted biopsy;
transrectal biopsy;
systematic biopsy;
diagnostic efficacy
- From:
Chinese Journal of Clinical Oncology
2025;52(4):183-187
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the diagnostic efficacy of transrectal conventional ultrasound-guided systematic biopsy and transrectal contrast-enhanced ultrasonography(CEUS)-guided targeted biopsy for suspected prostate cancer(PCa).Methods:A total of 239 patients with suspected PCa who were admitted to Shanghai Fengxian District Central Hospital between February 2021 and February 2024 were se-lected.Among them,139 patients who underwent transrectal CEUS-guided targeted biopsy were included in the CEUS group.The conven-tional group included 100 patients who underwent transrectal conventional ultrasound-guided biopsy(12-core biopsy).The detection rates of PCa and clinically significant prostate cancer(CsPCa)in the two groups were compared.The detection rates of PCa in different subgroups were also analyzed.Core number,positive single-core count,and biopsy-related complications were compared between the two groups.Results:Biopsy confirmed PCa in 75(53.96%)patients and benign lesions in 64(46.04%)patients in the CEUS group.In the conventional group,38(38.00%)patients had PCa,and 62(62.00%)had benign lesions.The detection rate of PCa in the CEUS group was significantly higher than that in the conventional group(P<0.05).There were statistically significant differences in the detection rate of PCa between the different age groups and patients with different prostate specific antigen(PSA)levels in the CEUS group(P<0.05).Moreover,there were stat-istically significant differences in the detection rate of PCa between patients with different PSA levels in the conventional group(P<0.05).For patients aged>70 years,the PCa detection rate in the CEUS group was significantly higher than that in the conventional group(P<0.05).When the PSA level was>20 ng/mL,the PCa detection rate in the CEUS group was significantly higher than that in the conventional group(P<0.05).When the prostate volume was 31-60 cm3,the detection rate of PCa in the CEUS group was significantly higher than that in the conventional group(P<0.05).The CEUS group received a total of 283 targeted punctures,whereas the conventional group received 1,200 systematic punctures.The positivity rate for a single core was significantly higher in the CEUS group than that in the conventional group(P<0.001).Biopsy-related complications were comparable between the two groups(P>0.05).Conclusions:Transrectal CEUS-guided targeted biopsy can achieve a high detection and single-core positive rate in the diagnosis of PCa,particularly in older patients with high PSA levels.Moreover,it is safe.
